ALDH1A1 抗体 (Internal Region)
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Quick Overview for ALDH1A1 抗体 (Internal Region) (ABIN374658)
抗原
See all ALDH1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to ALDH1.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-RELGEYGFHEYTE, from the internal region of the protein sequence
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anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 48-147) antibody
ALDH1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 2-501) antibodyALDH1A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibodyVerified ALDH1A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibodyALDH1A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) antibodyALDH1A1 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-110) antibodyALDH1A1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2B2G1 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibodyALDH1A1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-326) antibodyALDH1A1 适用: 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibodyALDH1A1 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 315-434) antibodyALDH1A1 适用: 人, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal ALDH1A1-1381 unconjugated
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应用备注
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Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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别名
- ALDH1
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背景
- ALDH1A1 is an aldehyde dehydrogenase able to oxidize a wide variety of aliphatic aldehydes (retinaldehyde, acetaldehyde, etc.) to the corresponding carboxylic acids (retinoic acid, acetic acid, etc.). ALDH1A1 (also known as RALDH1, ALDH1, or AHD2) is highly expressed in the dorsal retina, ventral midbrain (dopaminergic neurons), and hematopoietic stem cells. ALDH1A1 is involved in retinoic acid (RA) synthesis during vertebrate embryogenesis. ALDH1A1 is first detected at E9.0-E10.5 in cranial tissues (ventral mesencephalon, dorsal retina, thymic primordia, optic vesicles) and in the mesonephros. ALDH1A1 is also of interest in Parkinson's Disease (PD) being expressed in the the A9 dopaminergic (DA) neuronal group projecting to the dorsal striatum, this is the most vulnerable site in PD (Chung et al, 2005). Some studies also identify ALDH1A1 as a marker of cancer stem cells. Studies of breast cancer tissues showed that those that expressed a form of ALDH1A1 had the worst outcomes.Synonyms: ALDC, ALDH-E1, ALDH1A1, ALHDII, Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, PUMB1, RALDH1, Retinal dehydrogenase 1
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基因ID
- 216, 9606
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UniProt
- P00352
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途径
- Dopaminergic Neurogenesis
抗原
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