DCP1A 抗体 (C-Term)
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Quick Overview for DCP1A 抗体 (C-Term) (ABIN374653)
抗原
See all DCP1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to DCP1A.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-QVLTKNKDNHN, from the C Terminus of the protein sequence
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应用备注
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Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))
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别名
- DCP1A
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背景
- Dcp1a is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. Dcp1a binds DCP1B, DCP2, RENT1 and SMAD4 and forms part of a cytoplasmic complex containing proteins involved in mRNA decay, including XRN1 and LSM1.Synonyms: SMIF, Smad4-interacting transcriptional co-activator, Transcription factor SMIF, mRNA-decapping enzyme 1A
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基因ID
- 55802, 9606
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UniProt
- Q9NPI6
抗原
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