UCP1 抗体 (C-Term)
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Quick Overview for UCP1 抗体 (C-Term) (ABIN374628)
抗原
See all UCP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-EQLKRELSKS RQ
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特异性
- This antibody recognizes Thermogenin (UCP1).
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_068605.1
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.1 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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别名
- SLC25A7 / UCP1
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背景
- The uncoupling proteins (UCPs) are mitochondrial inner membrane proteins that are considered to be transporters functioning as enzymatic uncouplers of oxidative phosphorylation. They are capable of returning protons pumped by the respiratory chain to the mitochondrial matrix. Uncoupling proteins currently comprise UCP1, UCP2, UCP3, UCP4, and UCP5. UCP1 is a 32 kDa protein that is active as a proton channel forming dimer. It can bind purine nucleotides and is capable of being stimulated by fatty acids.Synonyms: Mitochondrial brown fat uncoupling protein 1, Solute carrier family 25 member 7, Thermogenin, UCP 1, UCP-1
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基因ID
- 7350, 9606
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UniProt
- P25874
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途径
- Proton Transport, Brown Fat Cell Differentiation
抗原
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