CBX3 抗体 (Internal Region)
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Quick Overview for CBX3 抗体 (Internal Region) (ABIN374619)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to Chromobox protein homolog 3. No cross-reactivity expected with HP1-alpha and HP1-beta.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-EAFLNSQKAGKEKD, from the internal region of the protein sequence
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应用备注
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Peptide ELISA: 1/32000. Western Blot: 0.3 - 1.0 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- CBX3
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背景
- HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.Synonyms: Chromobox protein homolog 3, HECH, HP1 gamma, HP1-gamma, HP1Hs-gamma, Heterochromatin protein 1 homolog gamma, Modifier 2 protein
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基因ID
- 11335, 9606
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UniProt
- Q13185
抗原
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