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CBX3 抗体 (Internal Region)

This anti-CBX3 antibody is a 山羊 多克隆 antibody detecting CBX3 in WB 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN374619
发货至: 中国

Quick Overview for CBX3 抗体 (Internal Region) (ABIN374619)

抗原

See all CBX3 抗体
CBX3 (Chromobox Homolog 3 (CBX3))

适用

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人, 小鼠, 大鼠, 犬

宿主

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山羊

克隆类型

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多克隆

标记

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This CBX3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    特异性

    This antibody reacts to Chromobox protein homolog 3. No cross-reactivity expected with HP1-alpha and HP1-beta.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-EAFLNSQKAGKEKD, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: 0.3 - 1.0 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CBX3 (Chromobox Homolog 3 (CBX3))

    别名

    CBX3

    背景

    HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.Synonyms: Chromobox protein homolog 3, HECH, HP1 gamma, HP1-gamma, HP1Hs-gamma, Heterochromatin protein 1 homolog gamma, Modifier 2 protein

    基因ID

    11335, 9606

    UniProt

    Q13185
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