CBX5 抗体 (Internal Region)
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Quick Overview for CBX5 抗体 (Internal Region) (ABIN374617)
抗原
See all CBX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody recognizes Human Chromobox protein homolog 5 (CBX5).
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence C-NKRKSNFSNSADDIK, from the internal region of the protein sequence according to NP_036249.1, NP_001120793.1, NP_001120794.1. .Remarks: Variants (NP_036249.1, NP_001120793.1, NP_001120794.1) encode the same protein
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anti-Chromobox Homolog 5 (CBX5) (Internal Region) antibody
Verified CBX5 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1B10B2 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3A11F8 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E11-3A10 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 8G6 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/128000. Western Blot: 0.03 - 0.1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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别名
- CBX5
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背景
- HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.Synonyms: Chromobox protein homolog 5, HP1 alpha, HP1-alpha, HP1A, Heterochromatin protein 1 homolog alpha, p25
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分子量
- 22.2 kDa (NP_036249.1)
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基因ID
- 23468, 9606
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UniProt
- P45973
抗原
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