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CNR2 抗体 (C-Term)

This anti-CNR2 antibody is a 山羊 多克隆 antibody detecting CNR2 in WB. Suitable for 人.
产品编号 ABIN374612
发货至: 中国
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Quick Overview for CNR2 抗体 (C-Term) (ABIN374612)

抗原

See all CNR2 抗体
CNR2 (Cannabinoid Receptor 2 (CNR2))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This CNR2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to Cannabinoid receptor 2.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-TETEADGKITPWPD, from the C Terminus of the protein sequence
  • 应用备注

    Peptide ELISA: 1/16000. Western Blot: 2 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CNR2 (Cannabinoid Receptor 2 (CNR2))

    别名

    Cannabinoid Receptor 2

    背景

    The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P / Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.Synonyms: CB-2, CB2, CNR2, CX5, hCB2

    基因ID

    1269, 9606

    UniProt

    P34972
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