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beta 2 Adrenergic Receptor 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects beta 2 Adrenergic Receptor in WB 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN374608
发货至: 中国
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Quick Overview for beta 2 Adrenergic Receptor 抗体 (C-Term) (ABIN374608)

抗原

See all beta 2 Adrenergic Receptor (ADRB2) 抗体
beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

适用

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宿主

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山羊

克隆类型

  • 142
  • 39
  • 2
多克隆

标记

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This beta 2 Adrenergic Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 25
    • 19
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    C-Term

    特异性

    This antibody recognizes Beta-2 Adrenergic Receptor.

    交叉反应 (详细)

    Species reactivity (expected):Canine (Dog).
    Species reactivity (tested):Human, Cow.

    纯化方法

    Affinity Chromatography

    免疫原

    Peptide with sequence C-HQGTVPSDNIDSQ, from the C Terminus of the protein sequence (NP_000015.1).
  • 应用备注

    Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

    别名

    beta-2 Adrenergic Receptor

    背景

    Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor

    分子量

    46.6kDa (NP_000015.1).

    基因ID

    154, 9606

    UniProt

    P07550

    途径

    cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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