Adenosine A2b Receptor 抗体 (C-Term)
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Quick Overview for Adenosine A2b Receptor 抗体 (C-Term) (ABIN374607)
抗原
See all Adenosine A2b Receptor (ADORA2B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- CQADVKSGNG Q
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特异性
- This anitbody recognizes Adenosine receptor A2b.
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纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence (NP_000667.1). Genename: ADORA2B
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应用备注
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Peptide ELISA: 1/4000. Western Blot. Immunohistochemistry on paraffin sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Adenosine A2b Receptor (ADORA2B)
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别名
- Adenosine Receptor A2b
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背景
- Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2B
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基因ID
- 136, 9606
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UniProt
- P29275
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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