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STX1A 抗体 (N-Term)

This anti-STX1A antibody is a 山羊 多克隆 antibody detecting STX1A in WB 和 EIA. Suitable for 人, 小鼠, 大鼠, Cow 和 犬.
产品编号 ABIN374595
发货至: 中国

Quick Overview for STX1A 抗体 (N-Term) (ABIN374595)

抗原

See all STX1A 抗体
STX1A (Syntaxin 1A (Brain) (STX1A))

适用

  • 70
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  • 37
  • 9
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  • 5
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  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 犬

宿主

  • 78
  • 7
  • 2
山羊

克隆类型

  • 70
  • 17
多克隆

标记

  • 49
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This STX1A antibody is un-conjugated

应用范围

  • 59
  • 28
  • 26
  • 18
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  • 13
  • 10
  • 8
  • 3
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 13
    • 7
    • 6
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    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    N-Term

    序列

    KDRTQELRTA KD-C

    特异性

    Please note this product is expected to recognize the products of 2 different genes STX1A (NP_004594.1and NP_001159375.1) and STX1B (NP_443106.1).

    交叉反应 (详细)

    Species reactivity (expected):Human, Rat, Canine, Bovine.
    Species reactivity (tested):Mouse.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the N Terminus of the protein sequence according to NP_004594.1, NP_001159375.1, NP_443106.1.
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: 0.01 - 0.03 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    STX1A (Syntaxin 1A (Brain) (STX1A))

    别名

    Syntaxin 1A / STX1A

    背景

    Syntaxin is a 35 kDa type II integral membrane protein localized to the plasma membrane at nerve terminals. Syntaxin was identified through its association with synaptotagmin and N-type calcium channel, a subtype of calcium channel on the plasma membrane important for neurotransmitter release. Homologs of syntaxin were identified in various eukaryotes ranging from yeast to human. Evidences for syntaxin's involvement in vesicular transport and neurotransmission include the requirement of its yeast homologs, SSO 1 and 2, in targeting and fusion of Golgi-derived vesicles with the plasma membrane. Syntaxin is also the target of clostridial neurotoxin C1 that block neurotransmitter release. The formation of 20S complex involves the interaction of VAMP with syntaxin through an ATP-dependent reaction modulated by synaptotagmin, SNAP-25, alpha-SNAP, and NSF.Synonyms: Neuron-specific antigen HPC-1, STX1, STX1B1, STX1B2, Syntaxin-1A, Syntaxin-1B, Syntaxin-1B1, Syntaxin-1B2

    基因ID

    6804

    NCBI登录号

    NP_001159375

    UniProt

    Q16623

    途径

    Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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