PVALB 抗体 (C-Term)
Quick Overview for PVALB 抗体 (C-Term) (ABIN374572)
抗原
See all PVALB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-GVDEFSTLVA ES
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特异性
- This antibody recognizes Parvalbumin.
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交叉反应 （详细）
- Species reactivity (tested):Human, Rat.
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_002845.1.
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anti-Parvalbumin (PVALB) (C-Term) antibody
Verified PVALB 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Parvalbumin (PVALB) (AA 2-110) antibodyPVALB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Parvalbumin (PVALB) antibodyPVALB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Parvalbumin (PVALB) antibodyMicroarray verified PVALB 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB572452 unconjugated
anti-Parvalbumin (PVALB) (C-Term) antibodyPVALB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parvalbumin (PVALB) (AA 1-110) antibodyPVALB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Parvalbumin (PVALB) antibodyMicroarray verified PVALB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB43780 unconjugated
anti-Parvalbumin (PVALB) antibodyMicroarray verified PVALB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB717794 unconjugated
anti-Parvalbumin (PVALB) antibodyMicroarray verified PVALB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB509822 unconjugated
anti-Parvalbumin (PVALB) antibodyMicroarray verified PVALB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB170005 unconjugated
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应用备注
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Peptide ELISA: 1/32000. Western Blot: 0.1-0.3 μg/mL. Approx 12 kDa band observed in Human Brain lysates (calculated MW of 12.2 kDa accordingto NP_002845.1). Approx 10-12 kDa band observed in rat skeletal muscle and in rat heart cells transfectedwith human PVALB, but not in untransfected rat heart cells. (1)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PVALB (Parvalbumin (PVALB))
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别名
- Parvalbumin alpha / PVALB
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背景
- Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
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基因ID
- 5816
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NCBI登录号
- NP_002845
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UniProt
- P20472
抗原
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