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PDX1 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects PDX1 in WB 和 IHC (p). It exhibits reactivity toward 人, 小鼠, 大鼠 和 Chimpanzee.
产品编号 ABIN374551
发货至: 中国
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Quick Overview for PDX1 抗体 (C-Term) (ABIN374551)

抗原

See all PDX1 抗体
PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

适用

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人, 小鼠, 大鼠, Chimpanzee

宿主

  • 133
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  • 2
山羊

克隆类型

  • 117
  • 26
多克隆

标记

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This PDX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    This antibody reacts to Insulin promoter factor 1.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-KSFKANLENPIRLA, from the C Terminus of the protein sequence
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: 0.1 - 1 μg/mL. Immunohistochemistry on paraffin sections: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

    别名

    Insulin Promoter Factor 1

    背景

    PDX1 (Pancrease/duodenum homeobox 1, Insulin promoter factor 1, IPF1, Islet/duodenum homeobox 1, IDX1, Somatatostatin transactivating factor 1, STF1, Insulin upstream factor 1, UUF1, Glucose-sensitive factor, GSF) activates transcription of the insulin and somatostain genes. PDX1 is required for maintaining the hormone-producing phenotype of the beta-cell.Synonyms: GSF, Glucose-sensitive factor, IDX-1, IPF-1, IPF1, IUF-1, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, PDX-1, PDX1, Pancreas/duodenum homeobox protein 1, STF-1, Somatostatin-transactivating factor 1

    基因ID

    3651

    NCBI登录号

    NP_000200

    UniProt

    P52945

    途径

    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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