APOE 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for APOE 抗体 (C-Term) (ABIN374539)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- C-VGTSAAPVPS DNH
-
特异性
- This antibody recognizes Apolipoprotein E (C-term).
-
交叉反应 (详细)
- Species reactivity (tested):Human.
-
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
-
免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_000032.1. Genename: APOE
-
-
-
-
应用备注
-
Peptide ELISA: 1/32000. Western blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- APOE (Apolipoprotein E (APOE))
-
别名
- Apolipoprotein E (Apo E)
-
背景
- Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE
-
基因ID
- 348, 9606
-
UniProt
- P02649
-
途径
- Regulation of Cell Size, Lipid Metabolism
抗原
-