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APOE 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects APOE in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN374539
发货至: 中国
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Quick Overview for APOE 抗体 (C-Term) (ABIN374539)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

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宿主

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山羊

克隆类型

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  • 55
多克隆

标记

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This APOE antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    序列

    C-VGTSAAPVPS DNH

    特异性

    This antibody recognizes Apolipoprotein E (C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the C Terminus of the protein sequence according to NP_000032.1. Genename: APOE
  • 应用备注

    Peptide ELISA: 1/32000. Western blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    Apolipoprotein E (Apo E)

    背景

    Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE

    基因ID

    348, 9606

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
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