Choline Acetyltransferase 抗体 (C-Term)
Quick Overview for Choline Acetyltransferase 抗体 (C-Term) (ABIN374515)
抗原
See all Choline Acetyltransferase (CHAT) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            特异性
- This antibody reacts to CHAT.
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                                            交叉反应 (详细)
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                        Species reactivity (expected):Canine, Porcine.
 Species reactivity (tested):Human.
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                                            纯化方法
- Affinity chromatography
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                                            免疫原
- Peptide with sequence CKEKATRPSQGHQP, from the C Terminus of the protein sequence
 
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                                            应用备注
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                        Peptide ELISA: 1/32000. Western Blot: 0.03 - 0.3 μg/mL. 
 Other applications not tested.
 Optimal dilutions are dependent on conditions and should be determined by the user.
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                                            限制
- 仅限研究用
 
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                                            浓度
- 0,5 mg/mL
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                                            缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freezing and thawing.
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                                            储存条件
- 4 °C/-20 °C
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                                            储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
 
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    - Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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                                            别名
- CHAT
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                                            背景
- Choline acetyltransferase (ChAT) catalyzes the synthesis of the neurotransmitter acetylcholine (ACh) from choline and acetyl-CoA in cholinergic neurons. ChAT serves as a specific marker for cholinergic neurons in both peripheral and central nervous systems. Dysfunction of cholinergic neurons underlies aspects of clinical symptoms found in neurological and psychiatric disorders such as Alzheimer's disease, Down and Rett syndromes. Choline acetyltransferase recruits choline for the synthesis of acetylcholine at preganglionic parasympathetic and sympathetic fibres. It is also present at parasympathetic postganglionic fibres.Synonyms: CHOACTase, ChAT, Choline O-acetyltransferase, Choline acetylase, EC=2.3.1.6
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                                            基因ID
- 1103
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                                            NCBI登录号
- NP_001136401
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                                            UniProt
- P28329
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                                            途径
- Skeletal Muscle Fiber Development
 抗原
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