UNC13D 抗体 (C-Term)
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Quick Overview for UNC13D 抗体 (C-Term) (ABIN374437)
抗原
See all UNC13D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-KQASQHALRP AP
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特异性
- This antibody recognizes Munc13-4/UNC13D.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide from the the C Terminus of the protein sequence according to NP_954712.1.
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anti-Unc-13 Homolog D (UNC13D) (AA 2-100) antibody
UNC13D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Unc-13 Homolog D (UNC13D) (Internal Region) antibodyVerified UNC13D 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 7-172) antibodyUNC13D 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) antibodyUNC13D 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyVerified UNC13D 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 891-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/16,000. Western Blot: 1-3 μg/mL. Approx.105 kDa band observed in Human T-lymphocyte and HeLalysates (calculated MW of 125 kDa according to NP_954712.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- UNC13D (Unc-13 Homolog D (UNC13D))
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别名
- UNC13D
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背景
- Secretion of the contents of cytolytic granules at the immunologic synapse is a highly regulated process essential for lymphocyte cytotoxicity. This process requires the rapid transfer of perforin containing lytic granules to the target cell interface, followed by their docking and fusion with the plasma membrane. Munc 13-4 localises with cytotoxic granules at the immunologic synapse. Munc 13-4 is essential for the priming step of cytolytic granule secretion preceding vesicle membrane fusion. There are two named isoforms.Synonyms: Munc13-4, Protein unc-13 homolog D
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基因ID
- 201294
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NCBI登录号
- NP_954712
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UniProt
- Q70J99
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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