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UNC13D 抗体 (C-Term)

UNC13D 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374437
发货至: 中国
  • 抗原 See all UNC13D 抗体
    UNC13D (Unc-13 Homolog D (UNC13D))
    抗原表位
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 25
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 21
    • 3
    • 2
    山羊
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 22
    • 2
    • 1
    • 1
    This UNC13D antibody is un-conjugated
    应用范围
    • 21
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    C-KQASQHALRP AP
    特异性
    This antibody recognizes Munc13-4/UNC13D.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide from the the C Terminus of the protein sequence according to NP_954712.1.
    Top Product
    Discover our top product UNC13D Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16,000. Western Blot: 1-3 μg/mL. Approx.105 kDa band observed in Human T-lymphocyte and HeLalysates (calculated MW of 125 kDa according to NP_954712.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    UNC13D (Unc-13 Homolog D (UNC13D))
    别名
    UNC13D (UNC13D 产品)
    别名
    FHL3 antibody, HLH3 antibody, HPLH3 antibody, Munc13-4 antibody, UNC13D antibody, 2610108D09Rik antibody, Jinx antibody, mFLJ00067 antibody, Unc13h4 antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, unc-13 homolog D antibody, unc-13 homolog D (C. elegans) antibody, transforming growth factor beta induced antibody, UNC13D antibody, Unc13d antibody, TGFBI antibody, unc13d antibody, un13d antibody
    背景
    Secretion of the contents of cytolytic granules at the immunologic synapse is a highly regulated process essential for lymphocyte cytotoxicity. This process requires the rapid transfer of perforin containing lytic granules to the target cell interface, followed by their docking and fusion with the plasma membrane. Munc 13-4 localises with cytotoxic granules at the immunologic synapse. Munc 13-4 is essential for the priming step of cytolytic granule secretion preceding vesicle membrane fusion. There are two named isoforms.Synonyms: Munc13-4, Protein unc-13 homolog D
    基因ID
    201294
    NCBI登录号
    NP_954712
    UniProt
    Q70J99
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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