RGS18 抗体 (C-Term)
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Quick Overview for RGS18 抗体 (C-Term) (ABIN374434)
抗原
See all RGS18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- CNEFQDVQSD VAIWL
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特异性
- This antibody recognizes RGS18.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide from the C Terminus of the protein sequence according to NP_570138.1
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亚型
- IgG
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anti-Regulator of G-Protein Signalling 18 (RGS18) (C-Term) antibody
Verified RGS18 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 28-84) antibodyRGS18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 1-235) antibodyRGS18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (N-Term) antibodyRGS18 适用: 人, 大鼠, 犬, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 41-90) antibodyRGS18 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 120-169) antibodyRGS18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: 1/16,000. Western Blot: 1-3 μg/mL. Approx 28 kDa band observed in Human Peripheral BloodMononucleocytes (lymphocytes) lysates (calculated MW of 27.8 kDa according toNP_570138.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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别名
- RGS18
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背景
- Regulators of G-protein signaling (RGSs) are a protein family that can act as GTPase-activating proteins for G(alphai)- and G(alphaq)-class proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination. One of these proteins, RGS18, is a 235 amino acid protein that is closely related to RGS5 (46 % identity) and approximately 30-40 % identity to other RGS proteins. This protein is expressed in platelet, leukocyte, and megakaryocyte cell lines. Engagement of TLR3 or TLR4 on monocyte-derived DCs potently down-regulates RGS18 and RGS14 without modifying other RGS proteins. A similar pattern of RGS protein expression occurs in immature bone marrow-derived mouse DCs stimulated to mature via TLR4 signaling. The changes in RGS18 and RGS1 expression are likely important for DC function.Synonyms: RGS13, Regulator of G-protein signaling 18
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基因ID
- 64407
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NCBI登录号
- NP_570138
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UniProt
- Q9NS28
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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