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NIR1 抗体 (C-Term)

The 山羊 多克隆 anti-NIR1 antibody (ABIN374424) specifically detects NIR1 in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 犬 samples.
产品编号 ABIN374424
发货至: 中国
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Quick Overview for NIR1 抗体 (C-Term) (ABIN374424)

抗原

See all NIR1 (PITPNM3) 抗体
NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

适用

人, 小鼠, 犬

宿主

  • 4
  • 1
山羊

克隆类型

  • 5
多克隆

标记

  • 5
This NIR1 antibody is un-conjugated

应用范围

  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    C-Term

    序列

    C-SWARGPPKFE SVP

    特异性

    This antibody detects NIR1 at C-term.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, DogSpecies reactivity (tested):Human

    纯化方法

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    免疫原

    Peptide from C Terminus of the protein sequence according to NP_112497.2, NP_001159438.1. Genename: PITPNM3
  • 应用备注

    Peptide ELISA: Limit dilution 1: 16000. Western blot: Preliminary experiments gave an approx 50 kDa band in Human Heart lysatesafter 0.1 μg/mL antibody staining. The 50 kDa band was successfully blocked by incubationwith the immunizing peptide. Immunohistochemistry: 5-10 μg/mL. In paraffin embeddedHuman Cerebral Cortex shows strong staining of cytoplasm in several neuronal cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • 抗原

    NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

    别名

    PITPNM3

    背景

    This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Membrane-associated phosphatidylinositol transfer protein 3, NIR-1, NIR1, PITPNM 3, Phosphatidylinositol transfer protein, Pyk2 N-terminal domain-interacting receptor 1, membrane-associated 3

    基因ID

    83394

    NCBI登录号

    NP_112497

    UniProt

    Q9BZ71
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