PITPNM1 抗体 (C-Term)
Quick Overview for PITPNM1 抗体 (C-Term) (ABIN374422)
抗原
See all PITPNM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-KARSISLKLD SEE
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特异性
- This antibody detects NIR2 at C-term and is expected to recognise both reported isoforms.
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交叉反应 （详细）
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Species reactivity (expected):Human, Dog, Cow.
Species reactivity (tested):Mouse. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide from the C-Terminus of the protein sequence according to NP_004901.2, NP_001124320.1. Genename: PITPNM1
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anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) antibody
PITPNM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) (C-Term) antibodyVerified PITPNM1 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) (AA 1-1243) antibodyPITPNM1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) (AA 117-166) antibodyPITPNM1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) (AA 110-190) antibodyPITPNM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) (N-Term) antibodyPITPNM1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) (AA 143-171), (N-Term) antibodyPITPNM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Limit dilution 1: 8000. Western blot: Customer's experiments gave a band at approx 160 kDa in lysates of a MouseMacrophage cell line after 2 μg/mL antibody staining (calculated MW of 130 kDa accordingto NP_004901.1). In ICC the customer found staining of vesicular cytoplasm in the samecell line.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PITPNM1 (Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1))
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别名
- NIR2
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背景
- NIR2 belongs to a family of proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis. A specific Thr residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking and distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration.Synonyms: DRES9, Membrane-associated phosphatidylinositol transfer protein 1, NIR2, PITPNM, PITPNM1
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基因ID
- 9600
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NCBI登录号
- NP_004901
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UniProt
- O00562
抗原
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