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PARD6A 抗体 (C-Term)

This anti-PARD6A antibody is a 山羊 多克隆 antibody detecting PARD6A in IHC (p). Suitable for 人.
产品编号 ABIN374388
发货至: 中国

Quick Overview for PARD6A 抗体 (C-Term) (ABIN374388)

抗原

See all PARD6A 抗体
PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This PARD6A antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    序列

    C-GSRIRGDGSG FSL

    特异性

    This antibody detects PARD6A at C-term. It is expected to recognise both reported isoforms (NP_058644.1, NP_001032358.1).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Syntehtic Peptide from C-Terminus of Human PARD6A Genename: PARD6A
  • 应用备注

    Peptide ELISA: antibody detection limit dilution 1: 8000. Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Pancreas, shows strongcytoplasmic staining in rare cells of intralobular ducts. Recommended concentration,10 μg/mL. Also tested in paraffin embedded Human Heart where it shows speckled stainingon myocardial fibres in transverse section.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

    别名

    PARD6A

    背景

    PAR6 is a cell membrane protein involved in cell polarization and asymmetrical cell division processes as part of a multi protein complex. It is thought to be involved in the invasive phenotype that is associated with metastatic carcinomas, playing a role in the epithelial to mesenchymal transition (EMT). PAR6 is also thought to be involved in the formation of epithelial tight junctions. PAR6 contains a semi Cdc42/Rac interactive binding (CRIB) domain and a PDZ (PSD95/Discs-large/ZO1) domain, and several different PAR6 isoforms have been identified.Synonyms: PAR-6, PAR-6 alpha, PAR-6A, PAR6A, PAR6C, Partitioning defective 6 homolog alpha, TIP-40, Tax interaction protein 40

    基因ID

    50855

    NCBI登录号

    NP_058644

    UniProt

    Q9NPB6

    途径

    Cell-Cell Junction Organization
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