ADAP1 抗体 (C-Term)
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Quick Overview for ADAP1 抗体 (C-Term) (ABIN374364)
抗原
See all ADAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-QEYAVEAHFK HKP
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特异性
- This antibody detects ADAP1 / CENTA1 at C-term.
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交叉反应 (详细)
- Species reactivity (expected):Rat, Dog, PigSpecies reactivity (tested):Human, Mouse
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_006860.1 Genename: ADAP1
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应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 40 kDa band observed in Human Brain and Mouse Brainlysates (calculated MW of 43.0 kDa according to NP_006860).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- ADAP1 (ArfGAP with Dual PH Domains 1 (ADAP1))
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别名
- ADAP1 / CENTA1
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背景
- The centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.Synonyms: Arf-GAP with dual PH domain-containing protein 1, Centaurin alpha 1, Centaurin-alpha-1, PM25, Putative MAPK-activating protein PM25
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基因ID
- 11033
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NCBI登录号
- NP_006860
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UniProt
- O75689
抗原
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