CARD11 抗体 (C-Term)
Quick Overview for CARD11 抗体 (C-Term) (ABIN374314)
抗原
See all CARD11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-QRKTIWVDED QL
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特异性
- This antibody detects CARD11 / CARMA1 at C-term.
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交叉反应 （详细）
- Species reactivity (expected):Mouse, Dog, CowSpecies reactivity (tested):Human
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from the C Terminus of the protein sequence according to NP_115791.3 Genename: CARD11
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anti-Caspase Recruitment Domain Family, Member 11 (CARD11) antibody
CARD11 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (C-Term) antibodyVerified CARD11 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (Internal Region) antibodyCARD11 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 481-580) antibodyCARD11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 1-221), (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western Blot: 1-3 μg/mL. Approx 150+65 kDa bands observed in lysates of cell line Jurkat(calculated MW of 135 kDa according to NP_115791.2). A similar pattern was observed inHEK293 transiently expressing CARD11. These bands are not observed in thenon-transfected HEK293.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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别名
- CARD11 / CARMA1
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背景
- CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
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基因ID
- 84433
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NCBI登录号
- NP_115791
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UniProt
- Q9BXL7
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
抗原
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