SETDB2 抗体 (N-Term)
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Quick Overview for SETDB2 抗体 (N-Term) (ABIN374283)
抗原
See all SETDB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GEKNGDAKTF WME-C
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特异性
- This antibody is expected to recognize both reported isoforms (NP_114121.2, NP_001153780.1).
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine (Dog), Porcine, Bovine.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography
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免疫原
- Synthetic peptide (GEKNGDAKTFWME-C) from the N-Terminus of the protein sequence according to NP_114121.2, NP_001153780.1. Genename: SETDB2
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应用备注
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Peptide ELISA: Limit dilution 1: 1000. Western blot: 0.3-1 μg/mL. Approx 80 kDa band observed in human heart lysates(calculated MW of 81.0 kDa according to NP_114121.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
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别名
- SETDB2 / CLLD8
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背景
- Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity.Synonyms: C13orf4, Chronic lymphocytic leukemia deletion region gene 8 protein, Histone-lysine N-methyltransferase SETDB2, KMT1F, Lysine N-methyltransferase 1F, SET domain bifurcated 2
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分子量
- 81.9 kDa (NP_114121.1)
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基因ID
- 83852
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NCBI登录号
- NP_114121
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UniProt
- Q96T68
抗原
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