HSPB8 抗体 (C-Term)
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Quick Overview for HSPB8 抗体 (C-Term) (ABIN374275)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NELPQDSQEV TCT
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特异性
- This antibody detects Heat shock protein beta-8 (HSPB8) at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_055180.1 Genename: HSPB8
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应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1 μg/mL. Approx 20-25 kDa band seen in human skeletal muscle lysate[Predicted MW of approx.25 kDa according to NP_055180].
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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别名
- HSPB8 / HSP22
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背景
- Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).Synonyms: Alpha-crystallin C chain, CRYAC, E2-induced gene 1 protein, E2IG1, Heat shock protein beta-8, Protein kinase H11, Small stress protein-like protein HSP22
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基因ID
- 26353
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NCBI登录号
- NP_055180
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UniProt
- Q9UJY1
抗原
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