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HSPB8 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects HSPB8 in WB 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN374275
发货至: 中国
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Quick Overview for HSPB8 抗体 (C-Term) (ABIN374275)

抗原

See all HSPB8 抗体
HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This HSPB8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    序列

    NELPQDSQEV TCT

    特异性

    This antibody detects Heat shock protein beta-8 (HSPB8) at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    免疫原

    Peptide from C Terminus of the protein sequence according to NP_055180.1 Genename: HSPB8
  • 应用备注

    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1 μg/mL. Approx 20-25 kDa band seen in human skeletal muscle lysate[Predicted MW of approx.25 kDa according to NP_055180].
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • 抗原

    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

    别名

    HSPB8 / HSP22

    背景

    Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).Synonyms: Alpha-crystallin C chain, CRYAC, E2-induced gene 1 protein, E2IG1, Heat shock protein beta-8, Protein kinase H11, Small stress protein-like protein HSP22

    基因ID

    26353

    NCBI登录号

    NP_055180

    UniProt

    Q9UJY1
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