GULP1 抗体 (C-Term)
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Quick Overview for GULP1 抗体 (C-Term) (ABIN374220)
抗原
See all GULP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EGTVFCLDPL DSRC
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特异性
- This antibody detetcs GULP / GULP1 at C-term.
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交叉反应 (详细)
- Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_057399.1. Genename: GULP1
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应用备注
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Peptide ELISA: Limit dilution 1: 64000. Western blot: 0.2-0.6 μg/mL. Approx 35 kDa band observed in Human Placenta lysates(calculated MW of 34.5 kDa according to NP_057399.1). Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Kidney shows staining ofcytoplasm, stronger in a selection of epithelial cells of distal convoluted tubules.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))
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别名
- GULP1 / CED6
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背景
- The prompt clearance of cells undergoing apoptosis is critical during embryonic development, normal tissue turnover, as well as inflammation and autoimmunity. CED6 and its human homologue gulp, encode an adapter protein, whose function in engulfment. The upstream and downstream components of CED6 mediated signaling are not known. Recently, CED1 has been shown to encode a transmembrane protein on phagocytic cells, with two functional sequence motifs in its cytoplasmic tail that are important for engulfment.Synonyms: CED-6, Cell death protein 6 homolog, PTB domain adapter protein CED-6, PTB domain-containing engulfment adapter protein 1
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基因ID
- 51454
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NCBI登录号
- NP_057399
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UniProt
- Q9UBP9
抗原
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