DAP3 抗体 (C-Term)
Quick Overview for DAP3 抗体 (C-Term) (ABIN374210)
抗原
See all DAP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NPSLLERHCA YL
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特异性
- This antibody is expected to recognise isoform 1 (NP_387506.1), isoform 2 (NP_001186779.1) and isoform 3 (NP_001186780.1). Reported variants represent identical protein (NP_387506.1, NP_004623.1, NP_001186778.1).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_387506.1, NP_004623.1 Genename: DAP3
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anti-Death-Associated Protein 3 (DAP3) (C-Term) antibody
Verified DAP3 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Death-Associated Protein 3 (DAP3) (AA 1-398) antibodyDAP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein 3 (DAP3) (AA 159-398) antibodyDAP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein 3 (DAP3) antibodyDAP3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein 3 (DAP3) (AA 237-343) antibodyDAP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B7 unconjugated
anti-Death-Associated Protein 3 (DAP3) (AA 151-250) antibodyDAP3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein 3 (DAP3) (AA 368-401), (C-Term) antibodyDAP3 适用: 人 WB 宿主: 兔 Polyclonal RB49646 unconjugated
anti-Death-Associated Protein 3 (DAP3) (C-Term) antibodyDAP3 适用: 人, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein 3 (DAP3) (AA 51-66) antibodyDAP3 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 42C617 unconjugated
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应用备注
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Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL. Approx 40-45 kDa band seen in HeLa lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DAP3 (Death-Associated Protein 3 (DAP3))
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别名
- DAP3 / MRPS29
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背景
- Death Associated Protein 3 (DAP3) is a 46 kDa protein carrying a potential nucleotide binding motif (P-loop) at its N-terminal region. The protein is widely expressed, and the expression is upregulated during membrane-receptor mediated apoptosis. In interferon-gamma and Fas induced apoptosis, DAP3 acts as a positive mediator by functioning downstream of the receptor signaling complex and upstream of the effector caspases. However, the mechanism for its function is largely unknown. Interestingly, the N-terminal 230 amino acid fragment of DAP3 alone protects cells from Fas induced cell death. The same region of DAP3 also serves as a binding site for the glucocorticoid receptor and mediates receptor functions.Synonyms: 28S ribosomal protein S29 mitochondrial, DAP-3, Death-associated protein 3, Ionizing radiation resistance conferring protein, MRP-S29
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基因ID
- 7818
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NCBI登录号
- NP_387506
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UniProt
- P51398
抗原
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