BCAP31 抗体 (C-Term)
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北京 101111
Quick Overview for BCAP31 抗体 (C-Term) (ABIN374194)
抗原
See all BCAP31 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-QAAVDGPMDK KEE
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特异性
- This antibody detects BCAP31 / BAP31 at C-term.
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_001132929.1, NP_005736.3, NP_001132913.1. Genename: BCAP31
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应用备注
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Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 30 kDa band observed in Human Placenta and Brain lysate(predicted MW of 20 kDa according to NP_005736).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))
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别名
- BCAP31 / BAP31
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背景
- BAP31 (B Cell Receptor Associated Protein, 28 kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo and hetero oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL2/BCLXL associated protein. In the C terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.Synonyms: 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31
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基因ID
- 10134
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NCBI登录号
- NP_001132929
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UniProt
- P51572
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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