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MARK4 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects MARK4 in WB. It exhibits reactivity toward 人.
产品编号 ABIN374191
发货至: 中国
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Quick Overview for MARK4 抗体 (C-Term) (ABIN374191)

抗原

See all MARK4 抗体
MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

适用

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宿主

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山羊

克隆类型

  • 58
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多克隆

标记

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This MARK4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    IKRKPPPGCS DSPGV

    特异性

    This antibody detects MARK4 at C-term.

    纯化方法

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    免疫原

    Peptide from the C Terminus of the protein sequence according to NP_113605.2. Genename: MARK4
  • 应用备注

    Peptide ELISA: Limit dilution 1: 128000. Western blot: 0.3-1 μg/mL. Approx 70 kDa band observed in human prostate lysates(calculated MW of 75.0 kDa according to NP_113605.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • 抗原

    MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

    别名

    MARK4

    背景

    MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells.Synonyms: MAP microtubule affinity-regulating kinase 4, MARKL1

    基因ID

    57787

    NCBI登录号

    NP_113605

    UniProt

    Q96L34
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