Annexin A2 抗体 (N-Term)
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Quick Overview for Annexin A2 抗体 (N-Term) (ABIN374164)
抗原
See all Annexin A2 (ANXA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- STVHEILCKL SLEGD
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特异性
- This antibody is expected to recognize both reported isoforms.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Cow, and Pig.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide from N Terminus of the protein sequence according to NP_001002858.1, NP_004030.1, NP_001002857.1, NP_001129487.1. Genename: ANXA2
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应用备注
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Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 35 kDa band observed in lysates of cell lines A431 andA549 (calculated MW of 38.6 kDa according to NP_004030.1 and NP_001002857.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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- Annexin A2 (ANXA2)
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别名
- Annexin A2 / ANXA2
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背景
- The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin II is a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: ANX2, ANX2L4, Annexin II, Annexin-2, CAL1H, Calpactin I heavy chain, Chromobindin-8, LPC2D, Lipocortin II, Placental anticoagulant protein IV, Protein I, p36
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基因ID
- 302
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NCBI登录号
- NP_001002858
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UniProt
- P07355
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途径
- S100 Proteins
抗原
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