Peptide ELISA: 1/16000. Western blot: 0.3 - 1 μg/mL. Approx 70 kDa band observed in lysates of Human SkeletalMuscle and of cell line HepG2 (calculated MW of 69.0 kDa according to NP_000243.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. Could be involved in a signal transduction pathway necessary for late myogenesis, although its ubiquitous expression suggests a wider function.