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DOCK1 抗体 (C-Term)

The 山羊 多克隆 anti-DOCK1 antibody is suitable to detect DOCK1 in samples from 人, 小鼠, 大鼠, Cow, 犬 和 Pig. It has been validated for WB.
产品编号 ABIN374114
发货至: 中国
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Quick Overview for DOCK1 抗体 (C-Term) (ABIN374114)

抗原

See all DOCK1 抗体
DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

适用

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人, 小鼠, 大鼠, Cow, 犬, Pig

宿主

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山羊

克隆类型

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多克隆

标记

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This DOCK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    C-TTRKQTSVDS GIVQ

    特异性

    This antibody detects DOCK1 at C-term.

    纯化方法

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    免疫原

    Peptide from C Terminus of the protein sequence according to NP_001371.1 Genename: DOCK1
  • 应用备注

    Western blot: 3-4 μg/mL. Approx 150-200 kDa band seen in A431 cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • 抗原

    DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

    别名

    DOCK1 / DOCK180

    背景

    The DOCK1 protein is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. It also functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. The GEF activity of the DOCK1 protein may be enhanced by ELMO1.Synonyms: 180 kDa protein downstream of CRK, Dedicator of cytokinesis protein 1

    基因ID

    1793

    NCBI登录号

    NP_001371

    UniProt

    Q14185

    途径

    Signaling of Hepatocyte Growth Factor Receptor
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