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BAIAP2 抗体 (C-Term, Isoform 3)

The 山羊 多克隆 anti-BAIAP2 antibody is suitable to detect BAIAP2 in samples from 人, 犬 和 Cow. It has been validated for WB.
产品编号 ABIN374111
发货至: 中国
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Quick Overview for BAIAP2 抗体 (C-Term, Isoform 3) (ABIN374111)

抗原

See all BAIAP2 抗体
BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

适用

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人, 犬, Cow

宿主

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  • 15
  • 1
山羊

克隆类型

  • 48
  • 14
多克隆

标记

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  • 1
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  • 1
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This BAIAP2 antibody is un-conjugated

应用范围

  • 47
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Western Blotting (WB)
  • 抗原表位

    • 15
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    C-Term, Isoform 3

    序列

    C-SMSSADVEVA RF

    特异性

    This antibody will recognise only one of three reported isoforms (NP_006331.1) (Isofom 3).

    交叉反应 (详细)

    Species reactivity (expected):Canine (Dog), Bovine.
    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide from the C-Terminus of the protein sequence according to NP_006331.1. Genename: BAIAP2
  • 应用备注

    Peptide ELISA: Limit dilution 1: 16000. Western blot: 1-3 μg/mL. Approx 55 kDa band observed in Human Brain (Cerebellum andFrontal Cortex) lysates (calculated MW of 57.5 kDa according to NP_006331.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
  • 抗原

    BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

    别名

    BAIAP2

    背景

    BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.Synonyms: BAI-associated protein 2, BAI1-associated protein 2, BAP2, Brain-specific angiogenesis inhibitor 1-associated protein 2, FLAF3, Fas ligand-associated factor 3, IRS-58, IRSp53, IRSp53/58, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa

    基因ID

    10458

    NCBI登录号

    NP_006331

    UniProt

    Q9UQB8
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