BAIAP2 抗体 (C-Term, Isoform 3)
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Quick Overview for BAIAP2 抗体 (C-Term, Isoform 3) (ABIN374111)
抗原
See all BAIAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term, Isoform 3
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序列
- C-SMSSADVEVA RF
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特异性
- This antibody will recognise only one of three reported isoforms (NP_006331.1) (Isofom 3).
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交叉反应 (详细)
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Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide from the C-Terminus of the protein sequence according to NP_006331.1. Genename: BAIAP2
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应用备注
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Peptide ELISA: Limit dilution 1: 16000. Western blot: 1-3 μg/mL. Approx 55 kDa band observed in Human Brain (Cerebellum andFrontal Cortex) lysates (calculated MW of 57.5 kDa according to NP_006331.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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- BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))
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别名
- BAIAP2
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背景
- BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.Synonyms: BAI-associated protein 2, BAI1-associated protein 2, BAP2, Brain-specific angiogenesis inhibitor 1-associated protein 2, FLAF3, Fas ligand-associated factor 3, IRS-58, IRSp53, IRSp53/58, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa
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基因ID
- 10458
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NCBI登录号
- NP_006331
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UniProt
- Q9UQB8
抗原
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