FYN 抗体 (N-Term)
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Quick Overview for FYN 抗体 (N-Term) (ABIN374105)
抗原
See all FYN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VQCKDKEATK LTE
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特异性
- This antibody is expected to recognise all three reported isoforms of FYN (NP_002028.1, NP_694592.1 and NP_694593.1).
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交叉反应 （详细）
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Species reactivity (expected):Rat, Canine (Dog), Pig, Cow.
Species reactivity (tested):Human, Mouse. -
纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from the N Terminus of the protein sequence according to NP_002028.1, NP_694592.1, NP_694593.1. Genename: FYN
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anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (AA 7-176) antibody
FYN 适用: 人, 小鼠 WB, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal FYN-01 unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibodyFYN 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (pTyr530) antibodyFYN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (AA 13-43) antibodyFYN 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (AA 1-537) antibodyFYN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (AA 13-43), (N-Term) antibodyFYN 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB03090 unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (AA 1-30) antibodyFYN 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (AA 1-90) antibodyFYN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A8 unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (AA 1-482) antibodyFYN 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3G11-F9 unconjugated
anti-FYN Oncogene Related To SRC, FGR, YES (FYN) (C-Term) antibodyFYN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.2-1 μg/mL. Approx 55-60 kDa band observed in Jurkat, A431 and NIH-3T3lysates (predicted MW of 60 kDa according to NP_002028.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))
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别名
- FYN
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背景
- Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59 kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1.Synonyms: Proto-oncogene tyrosine-protein kinase Fyn, Protooncogene Syn, SLK, p59-Fyn
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基因ID
- 2534
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NCBI登录号
- NP_002028
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UniProt
- P06241
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途径
- JAK/STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling
抗原
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