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ALDH1A1 抗体 (C-Term)

There is 1 publication for this product available. The 山羊 多克隆 anti-ALDH1A1 antibody is suitable to detect ALDH1A1 in samples from 人, 小鼠, 大鼠, Cow 和 犬. It has been validated for WB, IHC (p) 和 EIA.
Pubmed (1 reference)
产品编号 ABIN374078
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ALDH1A1 抗体 (C-Term) (ABIN374078)

抗原

See all ALDH1A1 抗体
ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

适用

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人, 小鼠, 大鼠, Cow, 犬

宿主

  • 107
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山羊

克隆类型

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多克隆

标记

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This ALDH1A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Discover our top product ALDH1A1 Primary Antibody

  • 抗原表位

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    C-Term

    序列

    C-EVKTVTVKIS QKNS

    特异性

    This antibody detects ALDH1 at C-term.

    交叉反应 （详细）

    Species reactivity (expected):Canine (Dog) and Cow.
    Species reactivity (tested):Human, Mouse and Rat.

    纯化方法

    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide from the C-Terminus of the protein according to NP_000680.2. Genename: ALDH1A1
  • anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 48-147) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 48-147) antibody

    ALDH1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 2-501) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 2-501) antibody

    ALDH1A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibody

    Verified ALDH1A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibody

    ALDH1A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) antibody

    ALDH1A1 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-110) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-110) antibody

    ALDH1A1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2B2G1 unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibody

    ALDH1A1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-326) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-326) antibody

    ALDH1A1 适用: 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibody

    ALDH1A1 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 1G6 unconjugated

    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 315-434) antibody
    anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 315-434) antibody

    ALDH1A1 适用: 人, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal ALDH1A1-1381 unconjugated

  • 应用备注

    Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.03-0.1 μg/mL. Approx 55 kDa band observed in human liver lysates(calculated MW of 54.5 kDa according to NP_000680.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用

  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Amann, Hofmann, Freudenberger, Holland-Cunz, Eichmüller, Bazhin: "Expression and activity of alcohol and aldehyde dehydrogenases in melanoma cells and in melanocytes." in: Journal of cellular biochemistry, Vol. 113, Issue 3, pp. 792-9, (2012) (PubMed).

  • 抗原

    ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

    别名

    ALDH1

    背景

    ALDH1A1 is an aldehyde dehydrogenase able to oxidize a wide variety of aliphatic aldehydes (retinaldehyde, acetaldehyde, etc.) to the corresponding carboxylic acids (retinoic acid, acetic acid, etc.). ALDH1A1 (also known as RALDH1, ALDH1, or AHD2) is highly expressed in the dorsal retina, ventral midbrain (dopaminergic neurons), and hematopoietic stem cells. ALDH1A1 is involved in retinoic acid (RA) synthesis during vertebrate embryogenesis. ALDH1A1 is first detected at E9.0-E10.5 in cranial tissues (ventral mesencephalon, dorsal retina, thymic primordia, optic vesicles) and in the mesonephros. ALDH1A1 is also of interest in Parkinson's Disease (PD) being expressed in the the A9 dopaminergic (DA) neuronal group projecting to the dorsal striatum, this is the most vulnerable site in PD (Chung et al, 2005). Some studies also identify ALDH1A1 as a marker of cancer stem cells. Studies of breast cancer tissues showed that those that expressed a form of ALDH1A1 had the worst outcomes.Synonyms: ALDC, ALDH-E1, ALDH1A1, ALHDII, Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, PUMB1, RALDH1, Retinal dehydrogenase 1

    基因ID

    216

    NCBI登录号

    NP_000680

    UniProt

    P00352

    途径

    Dopaminergic Neurogenesis
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