ALDH1A1 抗体 (C-Term)
(1 reference)-
- 抗原 See all ALDH1A1 抗体
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This ALDH1A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- C-EVKTVTVKIS QKNS
- 特异性
- This antibody detects ALDH1 at C-term.
- 交叉反应 （详细）
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Species reactivity (expected):Canine (Dog) and Cow.
Species reactivity (tested):Human, Mouse and Rat. - 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- 免疫原
- Peptide from the C-Terminus of the protein according to NP_000680.2. Genename: ALDH1A1
- Top Product
- Discover our top product ALDH1A1 Primary Antibody
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anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 48-147) antibody
ALDH1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 2-501) antibodyALDH1A1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibodyALDH1A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibodyVerified ALDH1A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) antibodyALDH1A1 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibodyALDH1A1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-110) antibodyALDH1A1 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 2B2G1 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-326) antibodyALDH1A1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 315-434) antibodyALDH1A1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ALDH1A1-1381 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibodyALDH1A1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1G6 unconjugated
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- 应用备注
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Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.03-0.1 μg/mL. Approx 55 kDa band observed in human liver lysates(calculated MW of 54.5 kDa according to NP_000680.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Expression and activity of alcohol and aldehyde dehydrogenases in melanoma cells and in melanocytes." in: Journal of cellular biochemistry, Vol. 113, Issue 3, pp. 792-9, (2012) (PubMed).
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: "Expression and activity of alcohol and aldehyde dehydrogenases in melanoma cells and in melanocytes." in: Journal of cellular biochemistry, Vol. 113, Issue 3, pp. 792-9, (2012) (PubMed).
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- 抗原
- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
- 别名
- ALDH1 (ALDH1A1 产品)
- 别名
- ALDC antibody, ALDH-E1 antibody, ALDH1 antibody, ALDH11 antibody, PUMB1 antibody, RALDH1 antibody, AL1A1 antibody, aldc antibody, aldh-e1 antibody, aldh1 antibody, aldh11 antibody, pumb1 antibody, raldh1 antibody, GGADHR antibody, ALDH1A1 antibody, ALDDH antibody, Ahd2 antibody, Aldh1 antibody, Aldh2 antibody, Ahd-2 antibody, Aldh1a2 antibody, E1 antibody, Raldh1 antibody, Aldh1a1 antibody, ALHDII antibody, RALDH 1 antibody, RalDH1 antibody, aldehyde dehydrogenase 1 family member A1 antibody, aldehyde dehydrogenase 1 family, member A1 antibody, aldehyde dehydrogenase 1 family member A1 L homeolog antibody, aldehyde dehydrogenase family 1, subfamily A1 antibody, aldehyde dehydrogenase antibody, retinal dehydrogenase 1 antibody, ALDH1A1 antibody, aldh1a1 antibody, Aldh1a1 antibody, aldh1a1.L antibody, aldH1 antibody, LOC100732581 antibody, LOC101822890 antibody
- 背景
- ALDH1A1 is an aldehyde dehydrogenase able to oxidize a wide variety of aliphatic aldehydes (retinaldehyde, acetaldehyde, etc.) to the corresponding carboxylic acids (retinoic acid, acetic acid, etc.). ALDH1A1 (also known as RALDH1, ALDH1, or AHD2) is highly expressed in the dorsal retina, ventral midbrain (dopaminergic neurons), and hematopoietic stem cells. ALDH1A1 is involved in retinoic acid (RA) synthesis during vertebrate embryogenesis. ALDH1A1 is first detected at E9.0-E10.5 in cranial tissues (ventral mesencephalon, dorsal retina, thymic primordia, optic vesicles) and in the mesonephros. ALDH1A1 is also of interest in Parkinson's Disease (PD) being expressed in the the A9 dopaminergic (DA) neuronal group projecting to the dorsal striatum, this is the most vulnerable site in PD (Chung et al, 2005). Some studies also identify ALDH1A1 as a marker of cancer stem cells. Studies of breast cancer tissues showed that those that expressed a form of ALDH1A1 had the worst outcomes.Synonyms: ALDC, ALDH-E1, ALDH1A1, ALHDII, Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, PUMB1, RALDH1, Retinal dehydrogenase 1
- 基因ID
- 216
- NCBI登录号
- NP_000680
- UniProt
- P00352
- 途径
- Dopaminergic Neurogenesis
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