KIF5A 抗体 (Center)
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Quick Overview for KIF5A 抗体 (Center) (ABIN372915)
抗原
See all KIF5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody reacts to Kinesin Family Member 5A (KIF5A).
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide - KLH conjugated corresponding to 20 amino acids from near the center of Human KIF5.
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亚型
- IgG
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anti-Kinesin Family Member 5A (KIF5A) (AA 933-1032) antibody
KIF5A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 5A (KIF5A) (C-Term) antibodyKIF5A 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 5A (KIF5A) (AA 657-706) antibodyKIF5A 适用: 人, 犬, 兔, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 5A (KIF5A) (AA 473-605) antibodyKIF5A 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 5A (KIF5A) (AA 823-1027) antibodyKIF5A 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 5A (KIF5A) (Middle Region) antibodyKIF5A 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 5A (KIF5A) (AA 2-211) antibodyKIF5A 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 5A (KIF5A) (C-Term) antibodyKIF5A 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5-1.0 μg/mL. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- KIF5A (Kinesin Family Member 5A (KIF5A))
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别名
- KIF5A
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背景
- Kinesins are microtubule-based motor proteins involved in the transport of organelles in eukaryotic cells. They typically consist of 2 identical, approximately 110- to 120-kD heavy chains and 2 identical, approximately 60- to 70-kD light chains. Kinesin heavy chain isoform 5A is a neuron-specific member of the kinesin 5 (Kif5) family, consisting of the heavy chains of conventional kinesins. Mutation in human homolog causes autosomal dominant spastic paraplegia 10. Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.Synonyms: KIF5A, Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, NKHC, NKHC1, Neuronal kinesin heavy chain
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分子量
- 110 kDa
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基因ID
- 3798
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NCBI登录号
- NP_004975
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UniProt
- Q12840
抗原
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