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IL-33 抗体 (Center)

This anti-IL-33 antibody is a 兔 多克隆 antibody detecting IL-33 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN372914
发货至: 中国

Quick Overview for IL-33 抗体 (Center) (ABIN372914)

抗原

See all IL-33 (IL33) 抗体
IL-33 (IL33) (Interleukin 33 (IL33))

适用

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人, 小鼠, 大鼠

宿主

  • 107
  • 38
  • 4
  • 2
  • 2
  • 1
  • 1

克隆类型

  • 113
  • 42
多克隆

标记

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This IL-33 antibody is un-conjugated

应用范围

  • 109
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  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 18
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    Center

    特异性

    This antibody recognizes Interleukin-33 (IL33).

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic peptide - KLH conjugated corresponding to a 19 amino acid peptide from near the center of Human IL33.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    IL-33 (IL33) (Interleukin 33 (IL33))

    别名

    Interleukin-33 (IL33)

    背景

    IL33 is a cytokine which belongs to the IL-1 superfamily, and it induces helper T cells to produce type 2 cytokines. This cytokine was previously named NF-HEV 'nuclear factor (NF) in high endothelial venules' (HEVs), as it was originally identified in these specialized cells. IL33 mediates its biological effects by interacting with the receptors ST2 and IL-1 Receptor Accessory Protein, activating intracellular molecules in the NF-kappaB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-4, IL-5 and IL-13) from polarized Th2 cells. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the the severe pathological changes observed in mucosal organs following administration of IL33.Synonyms: C9orf26, IL-1F11, IL-33, IL1F11, Interleukin-1 family member 11, NF-HEV, NFHEV, Nuclear factor from high endothelial venules

    基因ID

    90865

    NCBI登录号

    NP_001186569

    UniProt

    O95760

    途径

    Production of Molecular Mediator of Immune Response
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