Reticulon 4 抗体 (N-Term)
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Quick Overview for Reticulon 4 抗体 (N-Term) (ABIN372912)
抗原
See all Reticulon 4 (RTN4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to Neuroendocrine-specific Protein C (RTN4/NOGO).
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide - KLH conjugated corresponding to 23 amino acids from near the amino terminus of Human NOGO-A.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 0.5-1.0 μg/mL. Immunohistochemistry on Paraffin Sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Reticulon 4 (RTN4)
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别名
- Reticulon-4 / RTN4
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背景
- Adult mammalian axon regeneration is generally successful in the peripheral nervous system but poor in the central nervous system. Inhibition results from physical barriers imposed by glial scars, a lack of neurotrophic factors, and growth inhibitory molecules associated with myelin, the insulating axon sheath. These molecules include NI35, myelin associated glycoprotein, and Nogo (Neurite Outgrowth Inhibitor). Nogo is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in adults.Synonyms: Foocen, KIAA0886, NOGO, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Reticulon-5
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基因ID
- 57142
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NCBI登录号
- NP_008939
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UniProt
- Q9NQC3
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途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
抗原
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