IL27 抗体 (N-Term)
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Quick Overview for IL27 抗体 (N-Term) (ABIN372855)
抗原
See all IL27 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody recognizes Interleukin 27 (IL27).
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交叉反应 (详细)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide from Human IL27
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亚型
- IgG
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应用备注
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Immunohistochemistry on paraffin sections: 5 μg/mL. Immunocytochemistry. Western blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- IL27 (Interleukin-27 Subunit alpha (IL27))
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别名
- Interleukin-27 / IL27A
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背景
- IL27 is a recently discovered member of the IL6/IL12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL12 p35-related protein termed p28. IL27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL27 is involved in the regulation of immune processes.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
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基因ID
- 246778
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NCBI登录号
- NP_663634
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UniProt
- Q8NEV9
抗原
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