CXCR6 抗体
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北京 101111
Quick Overview for CXCR6 抗体 (ABIN372833)
抗原
See all CXCR6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to CXC Chemokine Receptor 6 (CXCR6).
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide
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亚型
- IgG
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应用备注
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Immunohistochemistry on paraffin sections: 2,5 μg/mL. Western blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL.
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-80 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer.
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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别名
- CD186 / CXCR6
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背景
- Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR
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基因ID
- 10663
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NCBI登录号
- NP_006555
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UniProt
- O00574
抗原
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