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PC 抗体 (Internal Region)

PC 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN372799
发货至: 中国
  • 抗原 See all PC 抗体
    PC (Pyruvate Carboxylase (PC))
    抗原表位
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 16
    • 15
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, Cow, 犬
    宿主
    • 23
    • 1
    • 1
    山羊
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    This PC antibody is un-conjugated
    应用范围
    • 24
    • 17
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes Pyruvate Carboxylase (PC).
    交叉反应 (详细)
    Species reactivity (expected):Bovine, Canine (Dog), Mouse, Porcine and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide (C-KFKEVKKAYVEANQ) from an Internal region of Human PC.
    亚型
    IgG
    Top Product
    Discover our top product PC Primary Antibody
  • 应用备注
    ELISA: 1/16000. Western blot: 0.03-0.1 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PC (Pyruvate Carboxylase (PC))
    别名
    Pyruvic Carboxylase (PC) (PC 产品)
    别名
    BcDNA antibody, BcDNA:GH06348 antibody, Dmel\\CG1516 antibody, PC antibody, pyc antibody, wu:fb82g08 antibody, wu:fj85g01 antibody, PCX antibody, BA4157 antibody, Pc antibody, Pcb antibody, PCB antibody, Pcx antibody, Pyruvate carboxylase antibody, pyruvate carboxylase b antibody, PYruvate Carboxylase antibody, pyruvate carboxylase antibody, pyruvate carboxylase Pyr1 antibody, PCB antibody, pcxb antibody, pyc-1 antibody, PC antibody, pyc antibody, pyr1 antibody, CNF00650 antibody, PYC1 antibody, Ndas_1152 antibody, Ilyop_2503 antibody, Calni_0495 antibody, Ftrac_1004 antibody, Plabr_3574 antibody, Sgly_2936 antibody, Celly_0558 antibody, Hipma_0131 antibody, Halhy_1567 antibody, Mesop_1269 antibody, Pcx antibody, Pc antibody
    背景
    Pyruvate Carboxylase (PC, PCB) requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. PCB is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.Synonyms: PCB, Pyruvate carboxylase mitochondrial
    基因ID
    5091
    NCBI登录号
    NP_000911
    UniProt
    P11498
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