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GOT1 抗体 (Internal Region)

GOT1 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN372773
发货至: 中国
  • 抗原 See all GOT1 抗体
    GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))
    抗原表位
    • 14
    • 10
    • 9
    • 9
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 69
    • 33
    • 17
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 70
    • 14
    • 4
    • 3
    • 1
    山羊
    克隆类型
    • 79
    • 13
    多克隆
    标记
    • 46
    • 17
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GOT1 antibody is un-conjugated
    应用范围
    • 75
    • 44
    • 31
    • 14
    • 13
    • 10
    • 10
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes Cytoplasmic Aspartate Aminotransferase (GOT1).
    交叉反应 (详细)
    Species reactivity (expected):Rat.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide (C-RSYRYWDAEKR) from an internal region of Human GOT1.
    亚型
    IgG
    Top Product
    Discover our top product GOT1 Primary Antibody
  • 应用备注
    ELISA: 1/4000. Western Blot: 0.01-0.1 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5-5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))
    别名
    GOT1 (GOT1 产品)
    别名
    ASTQTL1 antibody, GIG18 antibody, cAspAT antibody, cCAT antibody, AST antibody, ISSD antibody, NSD antibody, SD antibody, SIALIN antibody, SIASD antibody, SLD antibody, xr406 antibody, CASPAT antibody, ASPARTATE AMINOTRANSFERASE antibody, ATAAT antibody, MATERNAL EFFECT EMBRYO ARREST 17 antibody, MEE17 antibody, T26C19.9 antibody, T26C19_9 antibody, aspartate aminotransferase antibody, aatA antibody, 83.t00021 antibody, AI789014 antibody, Got-1 antibody, Aspat antibody, Gaspat antibody, AL022787 antibody, FABP-pm antibody, Got-2 antibody, mAspAT antibody, ASPATA antibody, glutamic-oxaloacetic transaminase 1 antibody, solute carrier family 17 member 5 antibody, glutamic-oxaloacetic transaminase 1 homeolog antibody, aspartate aminotransferase antibody, glutamic-oxaloacetic transaminase 1, soluble antibody, glutamic-oxaloacetic transaminase 2 antibody, glutamatic-oxaloacetic transaminase 2, mitochondrial antibody, GOT1 antibody, SLC17A5 antibody, got1.S antibody, AAT antibody, aspC antibody, EHI_006080 antibody, AST2 antibody, ast2 antibody, got1 antibody, Got1 antibody, GOT2 antibody, Got2 antibody
    背景
    Aspartate Aminotransferase [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate-dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80 % of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene. Serum GOT [with SGPT] levels are usually elevated in states of hepatocellular injury (injury to the liver cells), the highest levels are associated with hepatitis of a viral origin. High levels are also found after myocardial infarction, when SGPT levels are lower.Synonyms: Aspartate aminotransferase, Glutamate oxaloacetate transaminase 1, Transaminase A
    分子量
    46 kDa.
    基因ID
    2805
    NCBI登录号
    NP_002070
    UniProt
    P17174
    途径
    Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process
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