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PNPLA2 抗体 (Internal Region)

PNPLA2 适用: 人, 小鼠, 大鼠 IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN372772
发货至: 中国
  • 抗原 See all PNPLA2 抗体
    PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))
    抗原表位
    • 16
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 54
    • 43
    • 12
    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 5
    • 3
    • 2
    • 1
    山羊
    克隆类型
    • 60
    • 4
    多克隆
    标记
    • 33
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PNPLA2 antibody is un-conjugated
    应用范围
    • 43
    • 29
    • 14
    • 14
    • 13
    • 13
    • 4
    • 4
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes Patatin-Like Phospholipase Domain Containing 2 (PNPLA2).
    交叉反应 (详细)
    Species reactivity (expected):Human and Rat.
    Species reactivity (tested):Mouse.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide (C-NIIEVSKEARKR) from an internal region of Mouse PNPLA2.
    亚型
    IgG
    Top Product
    Discover our top product PNPLA2 Primary Antibody
  • 应用备注
    ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))
    别名
    PNPLA2 / ATGL (PNPLA2 产品)
    别名
    1110001C14Rik antibody, ATGL antibody, PEDF-R antibody, TTS-2.2 antibody, TTS2 antibody, iPLA2zeta antibody, PNPLA2 antibody, pnpla2 antibody, 0610039C21Rik antibody, Atgl antibody, RGD1309044 antibody, patatin like phospholipase domain containing 2 antibody, patatin-like phospholipase domain containing 2 antibody, PNPLA2 antibody, pnpla2 antibody, Pnpla2 antibody
    背景
    Adipose triglyceride lipase (ATGL) may function as a lipase and play a role in the adaptive response to a low energy state, such as fasting, by providing fatty acids to other tissues for oxidation. In addition, decreased expression of desnutrin in obesity models suggests its possible contribution to the pathophysiology of obesity. ATGL catalyzes the initial step in triglyceride hydrolysis in mammalian adipose tissue. ATGL contains a patatin domain common to plant acyl hydrolases. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammalsSynonyms: Adipose triglyceride lipase, Calcium-independent phospholipase A2, Desnutrin, FP17548, IPLA2-zeta, Patatin-like phospholipase domain-containing protein 2, Pigment epithelium-derived factor, TTS2.2, Transport-secretion protein 2
    基因ID
    57104
    NCBI登录号
    NP_065109
    UniProt
    Q96AD5
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