P4HB 抗体
Quick Overview for P4HB 抗体 (ABIN372745)
抗原
See all P4HB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes endogenous levels of total P4HB.
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交叉反应 (详细)
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Species reactivity (expected):Monkey, Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide conjugated to KLH derived from the sequence around Proline 329 of Human P4HB.
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亚型
- IgG
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应用备注
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Western Blot. Immunofluorescence. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM Sodium HEPES, pH 7.5, 150 mM Sodium Chloride, 0.1 mg/mL BSA, 50 % Glycerol
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
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别名
- PDI / P4HB
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背景
- P4HB, Prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds.Synonyms: Cellular thyroid hormone-binding protein, ER marker, ERBA2L, P4HB, PDI, PDIA1, PO4DB, Prolyl 4-hydroxylase subunit beta, Protein Disulfide Isomerase, Protein disulfide-isomerase, p55
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分子量
- 57 kDa.
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基因ID
- 5034
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NCBI登录号
- NP_000909
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UniProt
- P07237
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途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
抗原
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