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P4HB 抗体

This anti-P4HB antibody is a 兔 多克隆 antibody detecting P4HB in WB, IF 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN372745
发货至: 中国

Quick Overview for P4HB 抗体 (ABIN372745)

抗原

See all P4HB 抗体
P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This P4HB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    Recognizes endogenous levels of total P4HB.

    交叉反应 (详细)

    Species reactivity (expected):Monkey, Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic peptide conjugated to KLH derived from the sequence around Proline 329 of Human P4HB.

    亚型

    IgG
  • 应用备注

    Western Blot. Immunofluorescence. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM Sodium HEPES, pH 7.5, 150 mM Sodium Chloride, 0.1 mg/mL BSA, 50 % Glycerol

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

    别名

    PDI / P4HB

    背景

    P4HB, Prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds.Synonyms: Cellular thyroid hormone-binding protein, ER marker, ERBA2L, P4HB, PDI, PDIA1, PO4DB, Prolyl 4-hydroxylase subunit beta, Protein Disulfide Isomerase, Protein disulfide-isomerase, p55

    分子量

    57 kDa.

    基因ID

    5034

    NCBI登录号

    NP_000909

    UniProt

    P07237

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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