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Vimentin 抗体

VIM 适用: 人, 小鼠, 大鼠, 哺乳动物 WB, IF, IHC (fro) 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN372741
发货至: 中国
  • 抗原 See all Vimentin (VIM) 抗体
    Vimentin (VIM)
    适用
    • 332
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    人, 小鼠, 大鼠, 哺乳动物
    宿主
    • 190
    • 129
    • 8
    • 6
    • 4
    • 4
    • 2
    小鸡
    克隆类型
    • 197
    • 145
    多克隆
    标记
    • 199
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    This Vimentin antibody is un-conjugated
    应用范围
    • 281
    • 132
    • 98
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Specific for the ~50 kDa Vimentin protein.
    交叉反应 (详细)
    Species reactivity (expected):other Mammalian.
    Species reactivity (tested):Human, Mouse and Rat.
    纯化方法
    Ig Fraction
    免疫原
    Recombinant human Vimentin purified from E. coli.
    亚型
    Ig Fraction
    Top Product
    Discover our top product VIM Primary Antibody
  • 应用备注
    Western blotting: 1/1,000. Immunofluorescence: 1/500. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • Plitzko, Havemeyer, Kunze, Clement: "The pivotal role of the mitochondrial amidoxime reducing component 2 in protecting human cells against apoptotic effects of the base analog N6-hydroxylaminopurine." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10126-35, (2015) (PubMed).

    Kang, Taldone, Patel, Patel, Rodina, Gozman, Maharaj, Clement, Patel, Brodsky, Young, Chiosis: "Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70." in: Journal of medicinal chemistry, Vol. 57, Issue 4, pp. 1188-207, (2014) (PubMed).

    Kirane, Toombs, Ostapoff, Carbon, Zaknoen, Braunfeld, Schwarz, Burrows, Brekken: "Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 18, pp. 5031-42, (2012) (PubMed).

  • 抗原
    Vimentin (VIM)
    别名
    Vimentin (VIM 产品)
    别名
    CTRCT30 antibody, cb28 antibody, vime antibody, vim antibody, vim1 antibody, vim2 antibody, VIM antibody, Vimentin antibody, vim4 antibody, vimentin antibody, vimentin L homeolog antibody, vimentin S homeolog antibody, VIM antibody, Vim antibody, vim antibody, vim.L antibody, vim.S antibody
    背景
    Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).Synonyms: VIM
    基因ID
    81818
    NCBI登录号
    NP_112402
    UniProt
    P31000
    途径
    Caspase Cascade in Apoptosis
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