Tyrosine Hydroxylase 抗体
(6 references)Quick Overview for Tyrosine Hydroxylase 抗体 (ABIN372734)
抗原
See all Tyrosine Hydroxylase (TH) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the ~60k tyrosine hydroxylase protein. The antibody recognizes all mammalian and at least some non-mammalian forms of the enzyme in Western blots and in Immunohistochemistry/Immunofluorescence.
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交叉反应 （详细）
- Species reactivity (tested):Mammalia.
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- SDS-denatured rat tyrosine hydroxylase, purified from pheochromocytoma.
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亚型
- IgG
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anti-Tyrosine Hydroxylase (TH) (AA 101-165) antibody
TH 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 82-310) antibodyTH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer40) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer31) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) antibodyTH 适用: 人 WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 486-514) antibodyTH 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 34-301) antibodyTH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer19) antibodyTH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 193-222), (Middle Region) antibodyTH 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (C-Term) antibodyVerified TH 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blotting: 1/1,000. Immunofluorescence 1/1000 (Frozen Sections). Immunohistochemistry on Frozen Sections: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C or (in aliquots) at -80 °C for long term storage.
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: "Co-transplantation of human pancreatic islets with post-migratory neural crest stem cells increases β-cell proliferation and vascular and neural regrowth." in: The Journal of clinical endocrinology and metabolism, Vol. 100, Issue 4, pp. E583-90, (2015) (PubMed).
: "Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib." in: Carcinogenesis, Vol. 33, Issue 9, pp. 1639-46, (2012) (PubMed).
: "Striatal dopaminergic and serotonergic markers in human heroin users." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 24, Issue 5, pp. 561-7, (2001) (PubMed).
: "Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ." in: Journal of neurochemistry, Vol. 79, Issue 2, pp. 349-60, (2001) (PubMed).
: "Influence of light and neural circuitry on tyrosine hydroxylase phosphorylation in the rat retina." in: Journal of chemical neuroanatomy, Vol. 19, Issue 2, pp. 105-16, (2000) (PubMed).
: "Quantitation of tyrosine hydroxylase protein in the locus coeruleus from postmortem human brain." in: Journal of neuroscience methods, Vol. 99, Issue 1-2, pp. 37-44, (2000) (PubMed).
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: "Co-transplantation of human pancreatic islets with post-migratory neural crest stem cells increases β-cell proliferation and vascular and neural regrowth." in: The Journal of clinical endocrinology and metabolism, Vol. 100, Issue 4, pp. E583-90, (2015) (PubMed).
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- Tyrosine Hydroxylase (TH)
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别名
- Tyrosine 3-Monooxygenase (TH)
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背景
- Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000, Salvatore et al., 2001, Dunkley et al., 2004).Synonyms: TYH, Tyrosine 3-hydroxylase
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基因ID
- 25085
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NCBI登录号
- NP_036872
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UniProt
- P04177
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途径
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
抗原
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