SYT1 抗体 (pThr202)
Quick Overview for SYT1 抗体 (pThr202) (ABIN372724)
抗原
See all SYT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr202
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特异性
- This antibody recognizes the ~60k-62k synaptotagmin protein phosphorylated at Thr202 in Western Blots of Rat brain lysate. The immunolabeling is completely eliminated by lambda-phosphatase treatment.
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交叉反应 （详细）
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Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, non-Human Primate and Zebrafish.
Species reactivity (tested):Rat. -
纯化方法
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr202 of Synaptotagmin.
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亚型
- IgG
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anti-Synaptotagmin I (SYT1) (AA 1-422) antibody
SYT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 136-422) antibodySYT1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Synaptotagmin I (SYT1) (pSer309) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (AA 301-523) antibodySYT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Dot blot: 1/1,000. Western blot: 1/1,000. Immunohistochemistry: 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- SYT1 (Synaptotagmin I (SYT1))
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别名
- Synaptotagmin-1
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背景
- Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001, Wang et al., 2003). Moreover, recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999, Lee et al., 2004).Synonyms: SYT1, SYT2, SYT3, SYT4, SYT5
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基因ID
- 6857
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NCBI登录号
- NP_001129277
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UniProt
- P21579
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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