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SYT1 抗体

The 兔 多克隆 anti-SYT1 antibody (ABIN372723) specifically detects SYT1 in WB. The antibody is reactive with 人, 大鼠, 小鼠, Cow, 小鸡 和 Non-Human Primate samples.
产品编号 ABIN372723
发货至: 中国
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Quick Overview for SYT1 抗体 (ABIN372723)

抗原

See all SYT1 抗体
SYT1 (Synaptotagmin I (SYT1))

适用

  • 85
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人, 大鼠, 小鼠, Cow, 小鸡, Non-Human Primate

宿主

  • 89
  • 12
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  • 1
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克隆类型

  • 99
  • 25
多克隆

标记

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This SYT1 antibody is un-conjugated

应用范围

  • 73
  • 45
  • 37
  • 18
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  • 9
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Western Blotting (WB)
  • 特异性

    This antibody recognizes the ~65k Synaptotagmin I protein.

    交叉反应 (详细)

    Species reactivity (expected):Human, Mouse, Bovine, Chicken and non-Human Primates.
    Species reactivity (tested):Rat.

    纯化方法

    Affinity Chromatography.

    免疫原

    Synthetic peptide corresponding to amino acid residues within the Synaptotagmin-1 protein.

    亚型

    IgG
  • 应用备注

    Western blot: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原

    SYT1 (Synaptotagmin I (SYT1))

    别名

    Synaptotagmin-1

    背景

    Synaptotagmin-1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that Synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65

    基因ID

    6857

    NCBI登录号

    NP_001129277

    UniProt

    P21579

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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