SYT1 抗体
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北京 101111
Quick Overview for SYT1 抗体 (ABIN372723)
抗原
See all SYT1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes the ~65k Synaptotagmin I protein.
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交叉反应 (详细)
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Species reactivity (expected):Human, Mouse, Bovine, Chicken and non-Human Primates.
Species reactivity (tested):Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide corresponding to amino acid residues within the Synaptotagmin-1 protein.
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亚型
- IgG
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应用备注
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- SYT1 (Synaptotagmin I (SYT1))
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别名
- Synaptotagmin-1
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背景
- Synaptotagmin-1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that Synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
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基因ID
- 6857
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NCBI登录号
- NP_001129277
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UniProt
- P21579
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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