RPH3A 抗体 (C-Term)
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Quick Overview for RPH3A 抗体 (C-Term) (ABIN372709)
抗原
See all RPH3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody recognizes the ~82k Rabphilin-3A protein.
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交叉反应 (详细)
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Species reactivity (expected):Human, Bovine, Canine and non-Human Primates.
Species reactivity (tested):Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide corresponding to amino acid residues from the C-terminal region of Rabphilin-3A.
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亚型
- IgG
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应用备注
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- RPH3A (Rabphilin 3A (RPH3A))
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别名
- Rabphilin-3A / RPH3A
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背景
- Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001).Synonyms: Exophilin 1, Exophilin-1, KIAA0985, Rabphilin 3A
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基因ID
- 171039
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NCBI登录号
- NP_598202
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UniProt
- P47709
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途径
- Synaptic Vesicle Exocytosis
抗原
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