DLG4 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for DLG4 抗体 (N-Term) (ABIN372707)
抗原
See all DLG4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody recognizes the ~95k PSD95 protein.
-
交叉反应 (详细)
-
Species reactivity (expected):Human, Bovine, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat and Mouse. -
纯化方法
- Affinity Chromatography.
-
免疫原
- Peptide corresponding to amino acid residues from the N-terminal region of Rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
-
-
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
-
别名
- DLG4 / PSD95
-
背景
- PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004).Synonyms: DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90
-
基因ID
- 29495
-
NCBI登录号
- NP_062567
-
UniProt
- P31016
-
途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-