STK10-A 抗体 (pSer482, pSer486, pSer490)
Quick Overview for STK10-A 抗体 (pSer482, pSer486, pSer490) (ABIN372704)
抗原
See all STK10-A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer482, pSer486, pSer490
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特异性
- This antibody recognizes the ~120k PLKK protein phosphorylated at Ser482,486,490.
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交叉反应 （详细）
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Species reactivity (expected):Human, Mouse, Rat and Zebrafish.
Species reactivity (tested):Xenopus. -
纯化方法
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser482,486,490 of Xenopus polo-like kinase kinase (PLKK).
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亚型
- IgG
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anti-Serine/threonine Kinase 10 (STK10-A) (Internal Region) antibody
STK10-A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase 10 (STK10-A) (AA 12-144) antibodySTK10-A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Serine/threonine Kinase 10 (STK10-A) (AA 342-376) antibodySTK10-A 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB50040 unconjugated
anti-Serine/threonine Kinase 10 (STK10-A) (AA 692-721), (C-Term) antibodySTK10-A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3401 unconjugated
anti-Serine/threonine Kinase 10 (STK10-A) (C-Term) antibodySTK10-A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase 10 (STK10-A) (Internal Region) antibodySTK10-A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- STK10-A (Serine/threonine Kinase 10 (STK10-A))
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别名
- PLKK1
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背景
- Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.Synonyms: Polo-like kinase kinase 1, stk10, xPlkk1
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基因ID
- 373731
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NCBI登录号
- NP_001079164
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UniProt
- Q9YHC9
抗原
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