NEFM 抗体 (C-Term)
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Quick Overview for NEFM 抗体 (C-Term) (ABIN372674)
抗原
See all NEFM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody recognizes the ~145k Neurofilament M protein.
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交叉反应 (详细)
- Species reactivity (tested):Human, Chicken, Mouse and Rat.
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纯化方法
- Ig Fraction
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免疫原
- Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.
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亚型
- Ig Fraction
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应用备注
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Western blot: 1/1000. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- NEFM (Neurofilament Triplet M Protein (NEFM))
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别名
- Neurofilament M (160 kD)
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背景
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (Ref.1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (Ref.2).Synonyms: (Neuronal Marker), NEF3, NEFM, NF-M, Neurofilament 3, Neurofilament medium polypeptide
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基因ID
- 24588
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NCBI登录号
- NP_058725
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UniProt
- P12839
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途径
- Brown Fat Cell Differentiation
抗原
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