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GRIA2 抗体 (pSer880)

GRIA2 适用: 人, 大鼠, 小鼠, 斑马鱼, Non-Human Primate WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372656
发货至: 中国
  • 抗原 See all GRIA2 抗体
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    抗原表位
    • 29
    • 16
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    • 1
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    pSer880
    适用
    • 96
    • 72
    • 67
    • 11
    • 10
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    • 5
    • 5
    • 5
    • 5
    • 3
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    • 1
    人, 大鼠, 小鼠, 斑马鱼, Non-Human Primate
    宿主
    • 94
    • 10
    克隆类型
    • 82
    • 22
    多克隆
    标记
    • 52
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
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    • 1
    This GRIA2 antibody is un-conjugated
    应用范围
    • 80
    • 27
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    • 16
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    • 10
    • 8
    • 8
    • 6
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    Western Blotting (WB)
    特异性
    This antibody is specific for the ~100k phosphorylated at Ser880.
    交叉反应 (详细)
    Species reactivity (expected):Chicken, Human, Mouse, Zebrafish and non-Human Primates.
    Species reactivity (tested):Rat.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser880 of rat GluR2.
    亚型
    IgG
    Top Product
    Discover our top product GRIA2 Primary Antibody
  • 应用备注
    Western blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    别名
    Glutamate Receptor 2 / GLUR2 (GRIA2 产品)
    别名
    GLUR2 antibody, GLURB antibody, GluA2 antibody, GluR-K2 antibody, HBGR2 antibody, GluR-2 antibody, GluR-B antibody, Glur-2 antibody, Glur2 antibody, GluR2 antibody, gluR-B antibody, glur2a antibody, gria2.1 antibody, zfGRIA2[a] antibody, glur2 antibody, glutamate ionotropic receptor AMPA type subunit 2 antibody, glutamate receptor, ionotropic, AMPA 2 antibody, glutamate receptor, ionotropic, AMPA2 (alpha 2) antibody, glutamate receptor, ionotropic, AMPA 2a antibody, glutamate receptor, ionotropic, AMPA 2 S homeolog antibody, GRIA2 antibody, Gria2 antibody, gria2a antibody, gria2.S antibody
    背景
    The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990, Hollmann and Heinemann, 1994). The number of GluR2 subunits in the AMPA receptor complex affects the Ca2+ permeability, rectification and single-channel conductance of AMPA receptors. Ser880 has been identified as the PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1 (Matsuda et al., 1999)Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic
    基因ID
    29627
    NCBI登录号
    NP_001077280
    UniProt
    P19491
    途径
    PI3K-Akt Signaling
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